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March 16, 2012

Statins and Exercise

Statin drugs are known to help lower cholesterol. But a new study shows that statins also increase oxidative stress, a measure of cell damage, in muscle cells, making exercise more difficult. And in elite athletes, that oxidative stress is exponentially greater.

Also found while taking statins, glycogens or stored carbohydrates, which are processed in the liver, are less available to muscle cells. And mitochondria, the power generators for the cells, are dysfunctional, creating 25% less power than in unmedicated individuals.

“It seems possible that statins increase muscle damage” during and after exercise “and also interfere somewhat with the body’s ability to repair that damage,” says Dr. Paul Thompson, the chief of cardiology at Hartford Hospital in Connecticut and senior author of the study.

If you take a statins, consult with your doctor before engaging in an exercise program, or before terminating any medications.

Posted by linda at March 16, 2012 6:29 AM

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